Prize Recipients
2025 Prize
CAR T-cell Therapy
Prize Recipients:
Carl June, University of Pennsylvania Perelman School of Medicine • Bruce Levine, University of Pennsylvania Perelman School of Medicine • Isabelle Rivière, Takeda • Michel Sadelain, Columbia University
Citation: For developing chimeric antigen receptor (CAR) T-cell technology for personalized and scalable cancer immunotherapy. By genetically engineering a patient’s own immune cells, CAR T-cells precisely target and destroy cancer cells. CAR T-cell therapy has provided durable remission for tens of thousands of patients with otherwise incurable blood cancers.
Credit: University of Pennsylvania Perelman School of Medicine, Columbia University Irving Medical Center
For recipent bios, click here.
Past Recipients
2024
The T7 Expression System
F. William Studier, Brookhaven National Laboratory
Citation: For developing technology that uses components of the T7 bacteriophage for rapid, cell-free, and bacterial expression of any gene of interest. By enabling the production of critical proteins and RNAs on a massive scale, the T7 Expression System has accelerated biomedical research and has helped to extend millions of lives worldwide through its use in therapeutics, diagnostics, and vaccines, including the mRNA vaccines that protect against COVID-19.
2023
Efficient DNA Synthesis
Marvin H. Caruthers, University of Colorado
Citation: For developing methods enabling efficient, accurate synthesis of specified DNA and RNA sequences, making possible the genomic revolution in biological science and medicine and improving the lives of hundreds of millions of people globally through diagnostic tests and genetic medicines.